Sodium Borohydride - A Versatile Reducing Agent
نویسندگان
چکیده
منابع مشابه
A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid
Dithiothreitol (DTT) is the standard reagent for reducing disulfide bonds between and within biological molecules. At neutral pH, however, >99% of DTT thiol groups are protonated and thus unreactive. Herein, we report on (2S)-2-amino-1,4-dimercaptobutane (dithiobutylamine or DTBA), a dithiol that can be synthesized from l-aspartic acid in a few high-yielding steps that are amenable to a large-s...
متن کاملPolymer Supported Zinc Borohydride: A Stable, Efficient, Selective, and Regenerable Reducing Agent for Variety of Organic Compounds
The difficult to handle and store zinc borohydride, Zn(BH4)2, is stabilized by supporting it on polyvinylpyridine. This new mild, efficient, selective, and regenerable polymer supported borohydride reducing agent reduces a variety organic compounds such as, aldehydes, a-b-unsaturated carbonyl compounds, acid chlorides, epoxides, disu...
متن کاملInactivation of Tetracycline with Sodium Borohydride.
Recently we reported on the rapid inactivation of tetracycline by use of cupric-morpholine complex (Kaplan, Lannon, and Buckwalter, J. Pharm. Sci., 64, 163, 1965). This degradation procedure is used as part of an assay technique for kanamycin in the presence of tetracycline. We have since found that sodium borohydride (Metal Hydrides Inc., Beverly, Mass.) can substitute for cupric-morpholine co...
متن کاملThe reduction of cozymase by sodium borohydride.
Cozymase (diphosphopyridine nucleotide, DPN) has been assayed by a variety of biochemical and chemical methods (1). Among the simplest procedures has been the determination of the light absorption of reduced DPN at 340 rnp after reduction by sodium hydrosulfite. Since special precautions are required to remove completely the excess reducing agent which absorbs in this region, it appeared advant...
متن کاملThe Electroanalytical Determination of Sodium Borohydride Using a Gold Electrode
Sodium borohydride or sodium tetrahydroborate is used as a reducing agent in many organic and inorganic reactions. Therefore, the determination of sodium borohydride present in the system is of great importance. Borohydride releases hydrogen under appropriated conditions in the presence of a suitable catalyst. Since the amount of hydrogen emitted is proportional to the amount of borohydride, th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Synlett
سال: 2004
ISSN: 0936-5214,1437-2096
DOI: 10.1055/s-2004-837192